Resident Evil 2 remake Guides and Walkthrough

Our Resident Evil 2 remake guides and walkthrough will make sure you make it out of the world of survival horror alive. If you need to know where a key is, how to defeat a boss, or where to find collectibles, we’ve got you covered. We’ve poured over RE2 remake looking in every nook and cranny to find the info you need to fight Umbrella.

We’ve tried to avoid spoilers below, but unfortunately, it’s impossible not to include them at all. We’ll lead with the most spoiler-free guides and put a disclaimer before we list the ones that discuss major story points or reveals. Just to warn you, though, if you’re looking for a completely spoiler-free Resident Evil 2 remake experience, you may want to turn back now.

Resident Evil 2 remake – General guides

If you need to know about the basics of RE2 remake, here’s where to look. We show you how healing and gunpowder work, as well as other useful tips to those just starting out.

WARNING: Spoilers below!

Resident Evil 2 remake – Weapons guides

We give you the scoop on everything you’d want to know about things that go bang in Resident Evil 2 remake. We show you where every gun is located, and how you can upgrade them.

Resident Evil 2 remake – Key and item guides

Need to know where to find a key or what doors it unlocks? Are you stumped on how to use an item? Check out our guides below to get the help you need.

Resident Evil 2 remake – Boss guides

We tell you how to get through every boss encounter in these guides.

Resident Evil 2 remake walkthroughs

We take you all the way through the game in our detailed walkthroughs.

Resident Evil 2 remake – Collectibles and unlocks guides

We show you every single collectible and unlock and how to find them.

Resident Evil 2 remake – Misc. guides

These guides didn’t really fit into any of the above categories, but they still contain a ton of useful info.

For more Resident Evil 2 remake articles, check out our game hub.

Top 10 Most Gruesome Resident Evil Villains

Top 10 Most Gruesome Resident Evil Villains

Whether you're playing as Jill Valentine or the esteemed Leon S. Kennedy, the Resident Evil series always has unique foes to throw your way. Here is a quick summary of what you can expect as you work your way through the many mansions and labs of Umbrella Corps. (Some spoilers ahead!)
Alexia Ashford

A clone of a British noblewoman, Alexia injects herself with a strain of T-Virus while in cryosleep. The resulting monster is a blue-skinned boss that takes gunfire like a champ and spews fire. Only something as powerful as the Linear Launcher is able to take her down after a few mutations.
Dr. Salvador

Commonly referred to as the Chainsaw Man, the good doctor relentlessly chases Leon Kennedy through the streets of Spain in Resident Evil 4. Leon has to be quick on his feet and fast on the trigger to avoid decapitation. Just don't use a pistol, he can absorb those shots with ease.
Jack Krauser

Jack Krauser is an experienced military man who takes mercenary work on the side. This puts him into a partnership with Leon Kennedy as they take on the bioweapons in Resident Evil 4's Spain. Eventually, Jack succumbs to the virus, growing a nasty arm blade, and a violent temper.
Lisa Trevor

A mutated hunchback from the original Resident Evil, Lisa spent years undergoing Umbrella experiments. She drapes herself in the flesh of her victims, namely anyone unfortunate enough to be wandering the halls of the mansion. Distinctive features include uncanny eyeballs and a propensity for lunging at anything that moves.
Mimicry Marcus

A walking, grunting bomb of leeches, you don't want to get in close quarters with a Mimicry Marcus. Taking the form of James Marcus, it can stretch out its limbs for a whip attack or wrap them around you and start strangling. As it dies, it explodes into smaller enemies for you to take on.
Nemesis

There's a reason that Resident Evil 3 is subtitled Nemesis. This trenchcoat wearing creature hunts players all throughout the third entry in the series. Its unique visage and signature style made it popular. Nemesis eventually appeared with its rocket launcher as a playable character in the Marvel vs. Capcom series.
Neptune

Neptune may not be the biggest or the baddest Umbrella creation you'll face in RE, but he is a zombified shark. Any mad scientist creating abominations would at least consider creating shark monsters. So, of course, we have a whole breed of Neptunes swimming around. Watch out for the teeth.
Ramon Salazar

Ramon's distinctive look may cause some confusion. Despite his small stature and grey hair, he's just 20 years old at the time of Resident Evil 4. Setting off the events of the game by kidnapping the President's daughter, he's flanked at all times by a pair of imposing bodyguards.
Tyrant

The mass produced versions of the species of monster that also brought us Nemesis, these Tyrants served under Alfred Ashford during Code Veronica. While they're a little easier to take down, you'd probably rather be fighting run of the mill monsters. Thankfully, they haven't spread to the rest of the series. Yet.
William Birkin

A child prodigy and head researcher at Umbrella, William turns against his employer when he's looked over for a promotion. One game of plot later, he's a hulking monster with an eyeball shoulder pad and several forms to fight. Thus is the cycle of Resident Evil big bads.