| Agent Muriel Green |
Successfully complete "The Den of Souls" on the Hard difficulty setting |
| Antadurunnu |
Successfully complete "The God Seal" on the Hard difficulty setting |
| Arnold Leech |
Successfully complete "Al Khali" on the Easy or Normal difficulty setting |
| Bishop Malthus St. Claire |
Successfully complete "Crusades" on the Easy or Normal difficulty setting |
| Blind Behemoth |
Successfully complete "Morituri te salutant" on the Hard difficulty setting without being incapacitated |
| Brother William of Auxere |
Successfully complete "Motley Crew" on the Hard difficulty setting |
| Centurion Textius Longinus |
Successfully complete "Decadence" on the Hard difficulty setting without being incapacitated |
| Child Crusader |
Successfully complete "Crusades" on the Easy or Normal difficulty setting |
| Corpses Behemoth |
Successfully complete "River of Blood" on the Hard difficulty setting |
| Cpl. Simone Cole |
Successfully complete "The Tomb" on the Hard difficulty setting |
| Cpt. Devin Ross |
Kill 50 enemies using melee attacks |
| Cpt. Xavier Jones |
Successfully complete "Man Down" on the Hard difficulty setting |
| Crossbowman Crusader |
Successfully complete "Tortured Souls" on the Hard difficulty setting |
| Cultist |
Kill 100 enemies using melee attacks |
| Deceased Devin Ross |
Successfully complete "Still With You" on the Hard difficulty setting |
| Enlil |
Successfully complete "Spiritual Guide" on the Hard difficulty setting |
| Exlposive Cultist |
Disintegrate 50 enemies |
| Flamethrower |
Disintegrate 100 enemies |
| Fr. Paul Rawlings |
Pop 100 heads |
| Gladiator |
Successfully complete "Temple of Pain" on the Hard difficulty setting |
| Governor Cassus Vicus |
Successfully complete "Rome" on the Easy or Normal difficulty setting |
| Grenadier |
Kill 100 enemies using Ghost Bullet |
| Inanna |
Successfully complete "Skin" on the Hard difficulty setting |
| Ki |
Successfully complete "Flesh" on the Hard difficulty setting |
| Legionary |
Successfully complete "The Low Road" on the Hard difficulty setting |
| Lt. Abigail Black |
Kill 50 enemies using Ghost Bullet |
| Nanna |
Successfully complete "Blood" on the Hard difficulty setting |
| Ninlil |
Successfully complete "Skin" on the Hard difficulty setting without being incapacitated |
| Operation: Godseal |
Successfully complete "Exorcism" on the Hard difficulty setting |
| Psychic Commander |
Successfully complete "World War 2" on the Easy or Normal difficulty setting |
| Pyxis Prima |
Successfully complete "Sumeria" on the Easy or Normal difficulty setting |
| Sgt. Frank Delgado |
Pop 50 heads |
| Sgt. Wilhelmina "Billie" Church |
Successfully complete "Al Khali" on the Hard difficulty setting |
| Sir Richard de Gray |
Successfully complete "Out of the Frying Pan" on the Hard difficulty setting |
| Sumerian Puppet |
Successfully complete "Flesh" on the Hard difficulty setting without being incapacitated |
| The Jericho Team |
Successfully complete "Rivers of Blood" on the Hard difficulty setting without being incapacitated |
| Utu |
Successfully complete "Blood" on the Hard difficulty setting without being incapacitated |
| Warrior Crusader |
Successfully complete "Sewers" on the Hard difficulty setting |
